Table 2 is a summary of the results of the effects of uvaria chamae on plasma lipid profile in diabetic rats. The plant material was defatted with nhexane and 70% methanol. Antidiabetic and hypolipidemic activities of hydroethanolic root. Leaves aqueous extract of uvaria chamae was bacteriostatic on salmonella typhimurium atcc 14028 and salmonella spp. Pdf antibacterial activity of chalcone and dihydrochalcone. Files are available under licenses specified on their description page. Filed as uvaria chamae beauvais family annonaceae syntype of uvaria cylindrica schumach. Two known polyoxygenated cyclohexene derivatives, ferrudiol and zeylenol, and a new. Phytochemical composition, antioxidant and antibacterial. In tables 2 and 3, the antisickling activities glycosides is an indication that a recipe that contain u. Nov 15, 2016 the study showed that the hypoglycemic properties of uvaria chamae may be accounted for by the presence of the phytochemicals. Chamuvarinin, an acetogenin bearing a tetrahydropyran ring.
Evaluation of uvaria chamae aqueous and ethanolic extracts. For antioxidant property, free radicals scavenging capacity of the two extracts. Antihemolytic properties of extracts of six plants used in. A new cytotoxic acetogenin, chamuvarinin 1, containing a tetrahydropyran ring with an adjacent bistetrahydrofuran ring, which corresponds to a novel carbon skeleton in this series, was isolated from the roots of uvaria chamae, together with the previously reported acetogenins squamocin 2, desacetyluvaricin 3, and neoannonin 4. However, no scientific study has been conducted on the antidiabetic activity of this plant. The plasma cholesterol and ldl levels of diabetic rats treated with the extracts were significantly reduced p free media repository. Title african flowering plants database publication author website. Some of these biologically active secondary metabolites validate the claim made in traditional system of medicine. Beauv annonaceae offers alternative treatment for diabetes mellitus. Antiinflammatory activity of the aqueous macerate of. Pdf in vitro antisickling activities and phytochemical. Antiglycation, antioxidant, and cytotoxic activities of uvaria chamae. The common name refers to the fruit growing in its small bunches.
Antisickling activity, phytochemicals, plumbago zeylanica, sickle cell disease, uvaria chamae. Antiinflammatory activity of the aqueous macerate of leaves. Two known polyoxygenated cyclohexene derivatives, ferrudiol and zeylenol, and a new analog. Antidiabetic effects of the ethanolic root extract of. Phytochemical composition and antimicrobial activity of the.
We assure you that the result will be worthy of your time and money. Pdf comparative assessment of antibacterial activity of. Phytochemical composition and antimicrobial activity of the leaves of alchornea cordifolia schum and thonn, sanseviera liberica gerand labr and uvaria chamae p. Uvaria chamae root extract revealed the presence of saponnins, cardiac glycosides and terpenes tab. Beav annonaceae methanol root bark extracts were tested in vivo and in vitro. Uvaria chamae exhibited inhibitory activity table 2.
Phytochemical composition and biological activities of uvaria. Pdf phytochemical composition and biological activities of. Uvaria is a genus of flowering plants in the soursop family, annonaceae. The ethanolic extracts were tested for antiulcer activities uchamae showed a better anti ulcer activity on albino wistar rats compared tocimetidine a. Beauv revealed the presence of bioactive compounds consisting of flavonoids, alkaloids, tannins, saponins and phenolic compounds. Medicinal plants are the local heritage with global importance. Uvaria chamae was extracted with ethanol, and administered orally to rats at doses ranging from 200 to 5000 mgkgday for 28 days while distilled water was administered to the control group, the survived animals 43 %, were then euthanized, and blood collected for biochemical and haematological markers. Pdf phytochemical composition and biological activities of uvaria. Cytotoxic cbenzylated chalcone and other constituents of. Methanolic extracts of the root, stem and leaf of uvaria chamae were evaluated for their antibacterial activity against methicillinresistant staphylococcus aureus mrsa, staphylococcus aureus, escherichia coli, klebsiella spp, proteus spp, and. Chamuvaritin 20 is a dihydrobenzylchalcone isolated from uvaria chamae, an african medicinal plant used as purgative and febrifugal 38.
Uvaria chamae is a plant with both medicinal and nutritional values. Beauv and clerodendron splendens a cheval are known to have various medicinal and therapeutic properties. The implication of these results is in defining the role of each plant specimen in traditional recipes for scd management and drug development is presented. These consist mainly of essential oils, flavonoids, alkaloids and annonaceous acetogenins. Macro elemental composition of uvaria chamae leaves. This study presents antimicrobial properties of uvaria chamae roots, commonly used for the treatment of various infections in south benin.
Introduction free glutamate and bound with other amino acids into. Pdf a novel 1indanone isolated from uvaria afzelii roots. Pdf toxicological studies of herbal antitumor extract uvaria. The generic name uvaria is derived from the latin uva meaning grape, likely because the edible fruit of some species in the genus resemble grapes. In the present work phytochemical composition, antioxidant and antibacterial properties of aqueous and ethanol extracts of root of uvaria chamae were studied. A report has suggested a relationship between the free radical scavenging activity. Uvaria chamae on the kidney of albino rats, by measuring the levels of some electrolytes. Access is allocated within two business days of purchase and lasts one year. Free radical scavenging activity was evaluated using 2,2diphenyl1 picrylhydrazyl dpph radicals and inhibition of lipid peroxidation was accessed with thiobarbituric acid tba. This phytochemical was mutagenic in salmonella typhimurium strains ta98 and ta100 via the activation by the hepatic microsomal enzyme preparation.
The study aimed at evaluating antidiabetic activity of the ethanolic root extract of u. This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on multiresistant salmonella spp isolated in benin. Species are distributed throughout the old world tropics. The nmr was similar new benzyldihydrochalcones from uvaria chamae 1593 to that of chamuvarin in having a 2hs at 3. Pdf phytochemical composition and biological activities. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or. Pdf phytochemical composition, antioxidant and antibacterial.
Media in category uvaria chamae the following 2 files are in this category, out of 2 total. Uvaria chamae is a medicinal plant that is used in many parts of the world in the treatment of diabetes, and other diseases. Phytochemical composition and biological activities 555 preparation of plant extracts the leaves of clerodendron splendens and roots of uvarea chamae were airdried at the laboratory bench for 10 days and then ground into a uniform powder using a thomas wiley mill machine model ed 5 usa. Odewo, a taxonomist in the department of botany and microbiology, faculty of science, university of lagos, nigeria. The antifungal, antimalarial and antiinflammatory activities of uvaria chamae have also been reported 11, 14. Studies on the antiulcer properties of ethanolic leaf. Phytoconstituants of two extracts of uvaria chamae tannins, flavonoids, and. Department of plant science and biotechnology, michael okpara university of agriculture, umudike p.
The fruit carpels are in fingerlike clusters, the shape giving rise to many vernacular names translated as bush banana or the like implying wildness. Phytochemical screening and effect of ethanolic root extract. A novel 1indanone isolated from uvaria afzelii roots. Uvaria chamae annonaceae, is an essential oil bearing plant. Methanolic extracts of the root, stem and leaf of uvaria chamae were evaluated for their antibacterial activity against methicillinresistant staphylococcus aureus mrsa, staphylococcus aureus. Apart from saponins, all the other groups of compounds were revealed by the current phytochemical screening. Their antiinflammatory and oxytocic properties were assessed in this study. The leaf extract of the plant uvaria chamae family annonoceace was extracted with 70% ethanol, and the ethanolic extract were tested for antiulceractivities. For the extraction of the phenolic constituents, the fat free sample was boiled with. New benzyldihydrochalcones from uvaria chamae sciencedirect. This study aims to analyze the chemical compounds and evaluate the antiradical and antisalmonellaactivities of extracts from sarcocephalus latifolius, lannea barteri, uvaria chamae, parkia biglobosaand khaya senegalensis using respectively standards phytochemical methods, phosphomolybdates reduction method and micro dilution method in liquid medium associated with.
African journal of biotechnology in vitro antisickling. The roots of the plants were collected in the esan central region of edo state, nigeria. This study aims to analyze the chemical compounds and evaluate the antiradical and antisalmonellaactivities of extracts from sarcocephalus latifolius, lannea barteri, uvaria chamae, parkia biglobosaand khaya senegalensis using respectively standards phytochemical methods, phosphomolybdates reduction method and micro dilution method in liquid medium associated with plating on agar medium. Macro elemental composition of uvaria chamae leaves with abstract, chapter 15, references and questionnaire. The two extracts of plant showed significant p free radical. All structured data from the file and property namespaces is available under the creative commons cc0 license. Antibacterial parameters revealed that among the four bacteria tested, aqueous extract of uvaria chamae has bacteriostatic power against esbl strains mbcmic 16. Monosodium glutamate, uvaria chamae, tamoxifen, tumor markers, necrosis. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drugcandidate are thus tested. Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food. Usda, ars, germplasm resources information network. Isolation and characterization of compounds from the stem bark of uvaria rufa annonaceae 53 experiments of hmbc as shown in a and hh cosy in b established the final structure of benzyl benzoate. Methods aqueous macerated leaves of uvaria chamae identification and leaf powder of uvaria chamae the botanical identification was carried out at the national floristic center of the university felix houphouet boigny ivory coast. The efficacy of uvaria chamae plant species in herbal remedies may have come as a result of.
Their absence could be justified by the nature of the. Uvaria chamae, commonly known as finger root or bush banana belongs to the family annonaceae. In vivo antisalmonella activity of aqueous extracts leaves of uvaria chamae using chick models preliminary test. Phytochemical composition and antimicrobial activity of. Antidiabetic effects of the ethanolic root extract of uvaria chamae p. Uvaria chamae in the germplasm resources information network grin, u. Antibacterial activity of extracts of plant was evaluated on four bacterial strains e.
At a concentration of 400mgml the extracts of phyllanthus amartes and uvaria chamae produced zone diameter izd of 1 1 mm and 8mm respectively. Uvaria chamae is a climbing shrub or small tree growing up to 4 metres tall328. The drug benzyl benzoate used in antifungal preparations has a mutagenic compound, chamuvaritin, a benzyl dihydrochalcone that was isolated from uvaria chamae 10. Uvaria chamae is one of such plants used traditionally to treat diabetes. In vitro antiradical and antisalmonella activities of. Evaluation of invivo antisalmonella activity of uvaria. The various vernacular names mostly cover more than this one species. Odewo, a taxonomist in the department of botany and microbiology, faculty of. Review of literature phytochemical screening medicinal plants are best owed with large number of pharmaceutically useful compounds which can be studied for investigation of new drugs for many serious diseases like cancer, tumours, aids and many human degenerative diseases. However, research is needed to ascertain the beneficial and adverse effects of the consumption of the extract. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or small tree native to tropical west and central africa where it grows in wet and dry forests and coastal scrublands. Toxicological studies of herbal antitumor extract uvaria. This finding indicates the anticaries potentials of these plant extracts and their probable implication in the management of dental caries. Department of agriculture agricultural research service.
In this study, we evaluated the acute and subchronic oral toxicity and safety of the aqueous root extract of uvaria chamae in spraguedawley rats. It has been reported that extracts of uvaria chamae have mutagenic effects. Two new cbenzylated flavanones from uvaria chamae and c. The ld 50 value of the mice treated intraperitoneally with a single dose of 0. Uvaria chamae annonaceae, phyllantus amarus phyllantaceae and lantana camara verbenaceae are empirically alleged to be used as beninese medicinal plants in the treatment of salmonellosis. Evaluation of invivo anti salmonella activity of uvaria. Free radicals are highly reactive molecules generated during oxidation reactions which in turn initiate chain reactions resulting to.
Antidiabetic effects of the ethanolic root extract of uvaria. Antimicrobial susceptibility tests were performed against several multidrugresistant bacteria using the mueller hilton well agar diffusion method. The extracts and aspirin were found to inhibit carrageenaninduced paw oedema on albino rats and mice with a strong activity in aspirin having 80. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drug candidate are thus tested. Sep 29, 2011 madubunyi ii 2010 hepatoprotective activity of uvaria chamae root bark methanol extract against acetaminopheninduced liver lesions in rats. Documentation of wound healing plants in lagosnige ria. Antidiabeticeffectsoftheethanolicrootextractof uvaria. Please note that this is a trial program and may end. Diabetes mellitus has been a menace to mankind from time immemorial. Finding the best college admission essay help shouldnt be a big deal once you can fully understand the tips my immigration story essay of. Antidiabetic and hypolipidemic activities of hydroethanolic. The ld50 done in albino mice 20 25g showed safety margin above 5000mgkg.
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